Scientific Program

Final Program

You can view the full program in the link below. 

ISSVA "Debates & Updates" 2025 Schedule

This ISSVA Debates & Updates 2025 program is made up of accepted and invited cases. The case presentations listed here may be in listed in a different order on the final program. We will continue to update the schedule as more information is made available.

Wednesday 23 April

9:00am       Welcome Comments 
9:10am       AM Basics | Moderators: Nicole Revencu – Genetics (Belgium), Laurence M. Boon – Surgery (Belgium), Anne Marie Cahill – Interventional Radiology (United States)

• Genetics | Olivia Boccara (France), Florence Coulet (France)
• Surgery | Juan Carlos Lopez-Gutierrez (Spain), Connor Devine (United States)
• Interventional Radiology | Grégoire Boulouis (France) 

10:30am     Break
11:00am     Flash Updates | Moderators: June Wu (United States), Bas Verhoeven (Netherlands)

• Interventional Radiology | Raja Shaikh (United States)                   
• Surgery | Pablo Laje (United States)
• Oncology | Maroeska Te Loo (Netherlands)
• Pharmacology | Niina Kleiber (Canada)

12:30pm    Lunch Break
13:30pm    PM Specialty Breakout Sessions

• Surgery | Moderators: Gresham Richter (United States), Tony Penington (Australia), Laurence M. Boon (Belgium)
  • Introduction
  • Preliminary Talks
    • Defining Aims of Surgery in Vascular Anomalies | Tony Penington (Australia)
    • Working in a Multidisciplenary Team | Gresham Richter (United States)
    • Surgery Alone and Surgery in Combination Treatment | Laurence Boon (Belgium)
  • Panel
    • AVM in Brachialis | Tony Penington (Australia)
    • Manidbular Arteriovenous Malformations: An Intraosseous, Form Sparing, Approach | Gresham Richter (United States)
    • Embolization and Resection of a BRAF+ Tumor | Tara Rosenberg (United States)
    • Aggressive PTEN-Associated Craniofacial AVM, refractory to treatment | Miteshkumar Ramwani (United Kingdom)
• Interventional Radiology | Moderators: Annouk Bisdorff-Bresson (France), Walter Wohlgemuth (Germany)
  • Basics  
    • Defining Imaging Needs for IR Planning: What the IR Needs to Know Before a Procedure | Rene Müller-Wille (Austria)
    • Do’s and Don’ts: In Diagnostic Radiology and IR | Annouk Bisdorff Bresson (France) 
    • Do’s and don’ts: Trunks/Pelvic/Typical Complications | Walter Wohlgemuth (Germany)
  • How Do I Do It?
    • How Do I Treat Cervicofacial AVM Using Septor Micro-catheters and Liquid Embolization Material AVM’s | Annouk Bisdorff-Bresson (France)
    • How Do I Treat Fava Patients with Cryotherapy: Number of Sessions and Outcome Speaker | Raja Shaikh (United States)
    • How Do I Treat Large Pelvic AVMs by Arterial or Venous Approach | Walter Wohlgemuth (Germany)
    • How Do We Treat Mucosal and Oropharyngeal  VM with Endovenous Laser | Annouk Bisdorff Bresson (France)
    • How Do I Treat Slow Flow Malformations of Upper and Lower Extremities | Vanessa Franziska Schmidt (Germany)
• Oncology | Moderators: Denise Adams (United States), Emmanuel Seront (Belgium)
  • A comprehensive review of 20 years of sirolimus therapy in vascular malformations: sharing our experience, issues and challenges. | Denise Adams (United States) and Adrienne Hammill (United States)
  •  From Bench to Bedside: How Basic Science is Shaping the Future of Targeted and Combination Therapies | Carrie Shawber (United States) and June Wu (United States)  
  • Unraveling the Complexity of Targeted Therapies in vascular malformations. 
    • Starting with an illustrative case. | An Van Damme (Belgium) 
    • When Should Targeted Therapies Be Combined, and Which Combinations Work Best?
      • Combo of BRAF inhibitor and MEK Inhibitor | Sally J. Cohen-Cutler (United States)
      • Combo of MEK inhibitor and mTOR inhibitor | Emmanuel Seront (France)
      • If there is NO mutation found, which other therapies | Denise Adams (United States)
    • An illustrative of how to bridge Access and Affordability | Kelly Mulligan (United States)
• Pathology | Moderators: Michel Wassef (France), Sylvie Fraitag (France)
  • Atypical presentation of congenital hepatic hemangioma. | Paloma Triana (Spain)
  • Are orbit nodular vascular anomalies (cavernous “hemangioma” or “cavernoma”) better classified as cavernous venous malformations or cavernous angioleiomyomas? | Franck El-Sissy (France)
  • Deep-seated pyogenic granulomas in pediatric patients. | Valerie Carlberg (United States)
  • Unusual presentation of vascular malformation in Li-Fraumeni syndrome. Tyson C. Echols (United States)
  • Fusion positive lymphangioma. | David Carpentieri (United States)
  • Unmasking the mass. An intraosseous venous malformation mimicking malignancy. Dawn Eichenfield (United States)
  • When genetics corrects histological diagnosis. Sylvie Fraitag (France)
  • Questions about bone vascular anomalies. Michel Wassef (France)

15:30pm    Break
16:00pm    PM Specialty Breakout Sessions 

• Surgery | Moderators: Gresham Richter (United States), Tony Penington (Australia), Laurence M. Boon (Belgium)
  • Panel
    • Small, Localized Intramuscular VM | Laurence Boon (Belgium)
    • Optimizing surgical management of intramuscular venous malformation preoperative glue embolization | Julien Coulie (Belgium)
    • Intra-articular Venous Malformation with Severe LIC: Multidisciplinary Approach to Management | Shelly Crary (United States)
    • Cases of KneeReplacement in KT | Laurence Boon (Belgium), Tony Penington (Australia)
• Interventional Radiology | Moderators: Annouk Bisdorff-Bresson (France), Walter Wohlgemuth (Germany)
  • Best and BEET
    • Basics and history of BEST | Luis Mir (France)
    • BEET (Bleomycin Electro Embo Therapy) in Fast Flow Lesions: Which AVM Types, Technique and Results. How do I do it and how to avoid complications? | Walter Wohlgemuth (Germany)
  • What I Would Never Do Again: Some Spectacular Mistakes | Walter Wohlgemuth (Germany)/Gregoire Boulouis (France)/Annouk Bisdorff Bresson (France)
  • Is Recurrence Preprogrammed? | Walter Wohlgemuth (Germany)
  • Cases and Panel
    • Recurrent Mandibular AVM: Clinical Insights and Intervention Speaker | Qiangqiang Nie (China)       
    • Navigating the Complexities of Pediatric High-Flow AVMs: A Case Report on Gluteal Arteriovenous Malformation Management | Carlo Angello Sanchez Montaño (Mexico)
    • Squid, Ethanol and Laser Therapy in a Pediatric Patient with a Mixed Forearm AVM: A Multidisciplinary | Carlo Angello Sanchez Montaño (Mexico)
• Oncology | Moderators: Denise Adams (United States), Emmanuel Seront (Belgium)
  • Integrating Targeted Therapies with Surgical & Interventional Radiology Approaches  
    • Combination of targeted therapies with embolization and sclerotherapy | Maria Bom-Sucesso (Portugal)
  •  Long-Term Issues in the era of targeted therapies
    • From the physician side: what are the different long term side effect category (metabolic, vascular, dermatologic, …). | Emmanuel Seront (France)
    •  Fertility Considerations: How do we inform patients about potential impacts on fertility? Strategies for managing future pregnancies while on targeted therapies. | Ionela Iacobas (United States)
    • From the patient side: and What role do patient support groups play in long-term management? | Caroline Van den Bosch (Netherlands)
    • Debate Between the Speakers and Audience: What is Really Important for the Patient?
• Pathology | Moderators: Michel Wassef (France), Sylvie Fraitag (France)
  • NFATC2-rearranged osseous vascular neoplasm. | Thuy Phung (United States)
  • Hepatic vascular tumors and plumbing anomalies simplified. | Anita Gupta (United States)
  • Intramuscular vascular anomalies: practical approach. | Alyaa Al Ibraheemi (United States)
  • Thoracic Vascular Anomalies. | Isabel Colmenero (Spain)                

18:00pm   Welcome Reception

Thursday 24 April

8:00am      Meet the Experts Sessions

•  Surgery | Interventional Radiology | Oncology | Genetics

9:00am      Medical Treatment Goals | Denise Adams (United States), Emmanuel Seront (Belgium)

• Towards a personalized administration of sirolimus | Emmanuel Seront (Belgium)
• Vascular malformations with targetable genetic alternations: When, which, and how much medical therapy? | Beth Apsel Winger (United States)
• An Alternate Approach to AVMs | Alexandra Borst (United States)
• Role of MEK inhibitors in lymphatic disorders associated with Noonan's syndrome | Amanda Jacobson-Kelly (United States)
• Changes in height and weight in pediatric patients treated with alpelisib | Whitney Eng (United States)

10:00am    Coagulation Disorders | Anne Dompmartin (France), Joanna Mack (United States)

• Peri-sclerotherapy Anticoagulation Use: Are DOACs Noninferior? | Julia Segal (United States)
• Kaposiform Lymphangiomatosis (KLA) with Refractory Thrombocytopenia | Taizo Nakano (United States)
• Multidisciplinary treatment of DIC associated with Bockenheimer Disease | Li Hu (China)
• Safety and efficacy of direct oral anticoagulants in pediatric patients with venous malformations | Whitney Eng (United States)

11:00am    Break
11:30am    The Role of Patient Advocacy & Family Support Groups | Leo Schultze Kool (Netherlands), Caroline van den Bosch (Netherlands)

• Patient Support and Advocacy - How We Can Partner Better | Autumn Atkinson (Unite States)
• Patient Partnership in Clinical Networks: A Presentation on Patient-Clinician Collaboration and How to Enable It | Nora Lazaro (Spain)
• The Role of Patient Advocacy and Family Support Groups in professional societies. | Caroline van den Bosch (Netherlands)

12:15pm    How Do We Know if Therapies Work? Measuring Outcomes in Clinical Trials | Bryan Sisk (United States), Sally Cohen-Cutler (United States)

• Speakers | Anne Marie Cahill (United States), Bhuvna Setty (United States), Mikkel Kaltoft (Denmark), Michael Kelly (United States)

13:00pm    Lunch
14:00pm    Head and Neck AVM | Dov Goldenberg (Brazil), Jan Jaap Janssen (Netherlands)

• Surgical excision treatment without preop embolization in  lip AVMs as a first-line treatment, a single center experience | Didier Salvan (France)
• Complex Maxillofacial AVM - Endovascular Cure | Hassan Abdullah (Kuwait)
• Head and Neck vascular anomalies : a challenge for the anesthesiologist | Charlotte Thirion (Belgium)
• ISSVA 2025 - Two Cases of Combining Reversible Electroporation and Bleomycin in Treatment of Arteriovenous Malformations | Vanessa Franziska Schmidt (Germany)
• Aggressive PTEN-Associated Craniofacial AVM, refractory to treatment | Miteshkumar Ramwani (United Kingdom)
• Facial complex vascular malformation with features of fast and slow flow components | Rebecca Rossener (Brazil)

15:00pm    Optimizing the Multidisciplinary Care Model | Francine Blei (United States), Beth Drolet (United States), Carine Van Der Vleuten (Netherlands)

• Patient feedback on multidisciplinary Vascular Anomalies Clinic (=VAC) Is there a right way to build this : Multidisciplinary VAC patient clinic versus  VAC staff meetings ? | Florence Gizard (France)
• Factors Affecting Quality of Life in Patients with Vascular Anomalies: A Retrospective Review from a Single Institution | Neeraja Swaminathan (United States)
• The CHOP CVAP Balancing Act: Setting Thresholds for Medical Therapy vs. IR/Surgery | Shivangi Argade (United States)

16:00pm    Break
16:30pm    FAVA - Trunk/CF/Extremities | Rune Andersen (Norway), Julien Coulie (Belgium)

• 3 patients with misdiagnosed FAVAs | Sigurd Berger (Norway)
• Surgical resection of FAVA in lower extremities single center experience | Pär Gerwins (Sweden)
• Arteriovenous shunting in a case of Fibro-Adipose Vascular Anomaly/PROS | Mohammad Amarneh (United States)
• Sclerotherapy-Resistant VM's: FAVAs in disguise? | Andrew Liu (United States)
• Radiofrequency Ablation as an alternative treatment for symptoms control when cryoablation is not available for fibroadipose vascular anomaly in pediatric patients: Preliminary results | Dario Teplisky (Argentina)

17:30pm    VM Upper and Lower Extremities | Laurence M. Boon (Belgium), Samantha Spencer (United States)

• Surgical management of intra-articular knee VM in children | Julien Coulie (Belgium)
• Sonographic window to facilitate treatment of synovial venous malformation | Ahmad Alomari (United States)
• Surgical and postoperative management of isolated intramuscular venous malformations of lower limb | Donovan Debluts (Belgium)

Affiliate Meetings
13:00-14:00 - Vascular Anomalies Canada - Anomalies Vasculaires Canada | Scene GH
16:00-18:00 - Nursing Coordinators Meeting | Scene GH

Friday 25 April

8:00am      Meet the Experts Sessions

• Surgery | Interventional Radiology | Oncology | Pathology 

9:00am      Lymphatic Malformations | Juan Carlos Lopez-Gutierrez (Spain), Vittoria Baraldini (Italy)

• Congenital lymphatic malformation of the thigh | Tony Penington (Australia)
• Fertility Implications of a Large Mesenteric Lymphatic Malformation | Taumoha Ghosh (United States)
• Difficult Case: Nasal Tip Microcystic Lymphatic Malformation | Robert Chun (United States)
• Novel Treatment of Refractory Submandibular Lymphatic Malformations​ | Robert Chun (United States)
• Controversies in Neonatal Cervicofacial Lymphatic Malformation Management | Luke Jakubowski (United States)
• Multimodality Imaging Approach in Klippel-Trenaunay Syndrome Complicated with Lymphedema: A case report | Xingpeng Li (China)

10:00am    Lower Extremities AVM | Gilles Soulez (Canada), Michele Bigorre (France)

• A difficult case of an extensive high-flow malformation in right lower limb | Triana Paloma (Spain)
• CLOVES Syndrome treated with Sirolimus, Sclerotherapy, and Embolization : A Case Report | Mamiko Izumoto (Japan)
• Absolute Ethanol Intervention Resolving  Post-treatment complications of Exacerbation and Ulceration of a Left Foot AVM | Chen Hua (China)
• Fatal vascular tumor of the lower extremity: identification of PIK3CA mutation in utero from fetal plasma and prenatal use of sirolimus | Whitney Eng (United States)
• Management of Parkes Weber: Can Amputation Be Avoided? | Sara Kreimer (United States)- Use of Silk Suture for embolization in high flow vascular malformations | Haraldur Bjarnason (United States)

11:00am    Break
11:30am    Managing Fast Flow Vascular Lesions Mimicking AVMs | Laurent Guibaud (France), Xiaoxi Lin (China)

• Renal AVM in Pregnancy | Emily Bendel (United States)
• PHOST Case Report: Challenges in Complex Multidisciplinary Management | Dario Teplisky (Argentina)
• Rare subtype of soft tissue sarcoma mimicking craniofacial AVM in a teenage patient - can the mistake be avoided? | Ewa Bien (Poland)
• Potential etiology of arteriovenous shunt in PTEN hamartoma tumor syndrome (PHTS) | Ahmad Alomari (United States)
• Severe Manifestation of RASA1 Mutation: A Compelling Case Report | Joanna Mack (United States)
• CM-AVM2 Masquerading as an Overgrowth Syndrome | Elizabeth Neiman (United States)

12:30pm    Bone Lesions VM/LM/GLA | Gulraiz Chaudry (United States), Kiersten Ricci (United States)

• Complicated Oro-Mandibular Venous Malformation | Carol MacArthur (United States)
• The sinus pericrania | Xi Yang (China)
• A case of complex lymphatic anomaly (CLA) with extensive bone involvement | Claire O'Neill (United Kingdom)
• PROS and Osteosarcoma: A Treatment Dilemma | Alyssa Kesselman (United States)
• Management of Gorham-Stout Disease without Genotypic Confirmation | Sumukh Kumar (United States)

13:30pm    Lunch
14:30pm    Pathology/Genetics and Visceral/Bone Vascular Anomalies | Alyaa Al-Ibraheemi (United States), Sarah Sheppard (United States)

• A rare case of EWSR1::NFATC2-rearranged intravertebral vascular neoplasm | An-Katrien De Roo (Belgium)
• Unmasking the Rare Diagnosis of a Rapidly Progressing Vascular Skin Lesion with Visceral Involvement in a Newborn | Sally Cohen-Cutler (United States)
• A patient with atypical Kaposiform Lymphangiomatosis-like syndrome… with progression to Lymphangiosarcoma? | June Wu (United States), Carrie Shawber (United States)
• Hepatic angiosarcoma in a 4 yo female with history of multiple infantile hepatic hemangiomas | Hannele Salonen (Finland)
• Malignant Tumor Mimicking Slow Flow Vascular Malformations | Joyce Teng (United States)
• High Flow Lesions in the Tongue 2 cases | Alejandro Celis Jimenez (Mexico)

15:30pm    Clinical Skills in Vascular Anomalies Management | Maria Garzon (United States), Olivia Boccara (France)

• A hybrid lesion? (What is the diagnosis) | Mei Yoke Chan (Singapore)
• An Atypical case of Capillary Malformation | Emmanuel Seront (Belgium)
• Ras disorders masquerading as PROS: testing the genotype/phenotype correlation | Elizabeth Neiman (United States)
• The Utility of Biopsy in Indeterminate Vascular Malformations:  PHOST Initially Misdiagnosed | Anne Sailer (United States)
• Posterior Chest Wall Intramuscular Hemangioma | Anna Skochdopole (United States)

16:30pm    Closing Remarks
16:35pm    Closing Reception